Hi and thank you for your email.
There is one thing you can try, if you uninstall your software, after you have done this delete the following folders, assuming you have no other Pico software installed:
c:\Program Files\Pico Technology\
c:\Documents and Settings\xxxxxxx\Local Settings\Application Data\Pico Technology
where xxxxxx is your user id, also you may have to view hidden folders by clicking on Tools->Folder Options-> then choose the "View" Tab and where it says "Hidden files and folders" click on "Show hidden files and folders".
Then re-insall your software and see if this fixes your problem.
Let me know how you get on.