Although the December T&M News says Picoscope 18.104.22.168 for Linux will not work with Fedora >20, it DOES seem to work OK for me with Fedora 23 (64 bit, KDE desktop) using a Picoscope 3206A, providing as root you do
ln -s /usr/lib64/libgdiplus.so.0.0.0 /usr/lib64/libgdiplus.so
since the link to the unversioned libdgiplus is missing. Works fine on 3 quite different machines. On 32 bit systems I guess the link should be done in /usr/lib, though not checked this.