I have been using a picoscope model 3205 on linux mint for some years now. No problems at all. Very nice .
Now suddenly I can't get through to the picoscope box when starting the picoscope program. No contact at all and the LED is not flashing. I'm sure the hardware still works.
I'm using mono version: 4.2.1 on linux mint mate ver. 17.1 Rebecca and picoscope version 126.96.36.199.
I noticed that there are two updates close to each other... both 2015-11-14 and 2015-12-01, but I also updated to the latest version of mono recently. Are there any known problems?