What colour USB cable are you using?
Also, referring to the PicoScope 6 Self-Help Guide (http://www.picotech.com/document/pdf/picoscope6-self-help-guide-1.pdf
1. Does the PicoScope 2205 appear in the Windows Device Manager (see Section 1).
2. Please follow the instructions in section 3 to locate the trace.xml file - start PicoScope 6 with the PicoScope 6 connected, accept the option for Demo mode on start-up if it appears, then close PicoScope 6 and locate the file.