I have just migrated my Picoscope5203 from Win XP to a brand new Win 7 / 64bit laptop.
Good news: Installation went smooth and it is working.
Bad news: Several of the software menus and controls are partly cut off and some are thus not accessible.
Reason:
As modern laptops have extremely high display resolutions at small display sizes, I had to increase the Windows font size to 150% to being able to read text on the screen. Now apparently, the Picoscope6 software (PicoScope® 6 - PC Oscilloscope software version: 6.4.92.0) currently does not fully support scalable fonts. Font sizes do indeed increase, but some controls and menus keep their (small) predefined size.
Example: Left-clicking onto the bottom left "x1" ax control label will open a control, where the second edit box is almost completely cut off and thus not editable.